Biomedical Research in Cancer Stem Cells
Description
The research group focuses mainly on stress-related ageing in cells. Focusing on those which have a role in cancer, the laboratory develops genetic screenings based on detecting new genes related to cell proliferation. The research in this sense is based on using different cellular models: primary human cells, murine cells or immortalised cells capable of ageing.
It is working on identifying and characterising genes and microRNA in more aggressive breast tumours (triple negative); markers in laryngeal, pharyngeal and lung cancer with diagnostic value and a prognosis that help to target more specific chemotherapy treatment. Paying particular attention to breast cancer and its detection before clinical manifestation, the group is also studying new genes involved in cancer based on their identification in basic genetic traits.
Lorente Guerrero
